You may be wondering, “What Is THCV?” This article will explain what this substance is and what it does.
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THCV is a CB1 receptor antagonist and a non-intoxicating, mildly psychoactive drug. Here are some of its benefits and uses. Also, it may help treat osteoporosis and other bone-related problems.
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This article will explain the benefits and risks of THCV.
THCV
THCV is a crucial cannabinoid found in some cannabis strains. It is commonly present in low concentrations in most cannabis strains but has high levels in some. African sativas, such as Durban Poison, Red Congolese, and other landraces, are exceptionally high in THCV. THCV may also be present in a product if it has been laboratory-tested and is grown in a controlled environment.
However, the price of THCV products is similar to those of delta 9 THC. Some brands may cost a little more than the price of conventional THC products. Usually, the higher-quality THCV product will cost more. The supplements come in the form of gummies, capsules, and tinctures. The problem with many THCV products is that the extracts are not high enough in bioavailability and may contain useless ingredients.
CB1 receptor antagonist
A new drug called THCV is proving to be an effective anti-obesity treatment. The drug inhibits the effects of endogenous cannabinoids. It shares the same effect on the CB1 receptors as AM251, decreasing body weight in fasted and non-fasted mice. In addition, THCV reduces the weight of genetically obese mice.
This drug has several other pharmacological activities. It is a partial agonist for CB1 receptors, an activity shared with THC and CBG. This activity helps explain THCV’s effect on inflammation and inflammatory pain. It also inhibits neurotransmission and reduces seizures in rat models. Hence, THCV is a promising candidate for treating chronic liver disease.
Non-intoxicating
Although it is not intoxicating, the psychoactive component of THCV does not make you high per se. Instead, it produces a mild psychoactive effect that provides a short-lived energy boost and heightened mental clarity. THCV may be useful for combating fatigue and lack of concentration. Nevertheless, its potential to be a gateway drug is not clear. Let’s examine whether THCV is a safe alternative to THC.
In addition to its anti-diabetic properties, THCV is also known to lower glucose levels in the blood and improve blood sugar-regulating mechanisms. As such, it may have therapeutic potential in treating Type 2 Diabetes. Finally, THCV may also exert anticonvulsant and anti-epileptic effects, making it an essential tool in fighting chronic seizures and over-excitation of the nervous system. Furthermore, it may also help combat addiction by inhibiting the brain’s nicotine-seeking impulses.
Mildly psychoactive
While THC and THCV have similar chemical structures and psychoactive effects, THCv is found in relatively low amounts in marijuana. Scientists are only now beginning to understand this unique cannabinoid and are developing breeding experiments for strains containing it. Here are some interesting findings:
Although THCV is mildly psychoactive, it has energy-boosting solid properties. Many athletes and students have found that taking it has an energy boost. Its effects are much more cerebral than delta 8 THC. Users report feeling relaxed, alert, and clear-headed after ingesting the drug. THCV, however, does not appear to impact headspace, although some researchers have found perceptual differences between THCV and THC users.
Effects on appetite
While research is limited, a recent study suggests THCV may help reduce appetite and blood sugar levels. In mice, a study of pure THCV reduced appetite, while that of mice treated with a mixture did not show the same result. These findings suggest THCV may help regulate blood sugar levels and prevent obesity. Those who consume weed are less likely to be obese, but they should exercise caution to avoid munchies and overeating.
In animal studies, THCV may inhibit the signaling pathways of endogenous endocannabinoids by decreasing the number of receptors that activate them. It may also interact with other receptor sites, including G-protein-coupled receptors (GPR55) and transient receptor potential vanilloid 1 (TRPV1), and compete for the same site in the brain.
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THCV may reduce the adverse effects of marijuana in humans, including increased heart rate and subjective feelings of intoxication.
Legality
The legality of THCV in the United States is in doubt, as the substance does not fall under the CSA’s definition of “cannabimimetic agent” or “tetrahydrocannabinol,” which prohibits the sale and possession of marijuana and cannabis products. However, THCV may be legal in the United States is extracted from industrial hemp because it has less than 0.3 percent THC. Additionally, while THCV may be classified as an analog of THC under the Federal Analogue Act, current experts believe it is sufficiently different to avoid being treated as an analogue of THC.
While THCV is not a psychoactive substance, it does have medical benefits. It has been linked to treating Parkinson’s disease and epilepsy, in particular. Researchers have found that chronic THCV administration significantly attenuated the motor inhibition associated with Parkinson’s disease, delaying its progression and slowing the loss of neurons in the midbrain. Because it is similar in structure to THC, the legality of THCV in the United States is in doubt, although it has been used in several medical settings.
